PYC

PYC THERAP FPO [PYC]
PYC Therapeutics Limited, a clinical stage drug-development company, engages in the discovery and development of novel RNA therapeutics for the treatment of genetic diseases in Australia. It is developing PYC-003, which is in Phase1a/1b multiple ascending dose study for polycystic kidney disease; PYC-002, a Phelan McDermid Syndrome; PYC-001 for the treatment of Phelan-McDermid Syndrome; PYC-001, which is in Phase 1b multiple ascending dose study for autosomal dominant optic atrophy; and VP-001 for the treatment of retinitis pigmentosa type 11. The company was formerly known as Phylogica Limited and changed its name to PYC Therapeutics Limited in November 2019. PYC Therapeutics Limited was incorporated in 2001 and is based in Nedlands, Australia.
Healthcare · ASX Small Cap
$2.4200 -3.2%

Updated 9 Sep 2026 · Signals refresh every scan

Appeared in 2 consecutive scansFirst seen: 2026-03-13
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Active Signals

Bullish Signals

  • Trading above both moving averages — the trend is your friend here
  • Above-average volume (1.6x) on a red day — sellers in control
  • Drifting lower — down 5.8% over the last 5 days
  • Beating the Small Ords index — relative strength of 1.15, so it's outpacing the pack
  • Trading above the 200-day average — the long-term trend is on your side
  • Strong cash runway (40 quarters)
  • Very high P/S ratio (94.6x)
  • Strong revenue growth (+47%)
  • EPS estimates revised downward (-10pts)
  • Near 52-week high (93% of range)
  • Substantial holder(s) ceased (1)
  • CANSLIM N: Near 52-week high (breakout territory)
  • CANSLIM I: Institutional ownership (16%)
  • Sentiment is mixed — no strong consensus either way
  • Strong long-term momentum — up 63% over the past year (excluding last month)
  • Excellent risk-adjusted returns — Sharpe of 1.7 means strong gains without wild swings
  • Revenue growing at +47% — the top line is moving in the right direction
  • The bigger volume days are the up days — volume-weighted momentum is positive (1.64%/day)
  • RBA hiking (-3pts)

Risk Signals

  • Deeply negative margins (-167%)
  • Not enough chatter to gauge sentiment — defaulting to neutral

Expected next for PYC

14 Oct 2026Quarterly Cash Flow Report (4C)Estimated from past filings
Window: 7 Oct to 21 Oct
The last 4 moved PYC +3.4% on the day, on average — an observation, not a guide to what happens next.
Each date is labelled with how it is known. A date estimated from past filings is inferred from this company's own filing rhythm — it is not a confirmed date and not a statement about what the company intends to do. See the whole ASX calendar →

Recent Catalysts

NONE S&P DJI Announces September 2026 Quarterly Rebalance
NONE Investor Webinar Presentation Q3 2026
NONE ADOA Program - Data Presentation
HIGH Ceasing to be a substantial holder

Recent ASX Announcements

2026-09-04 S&P DJI Announces September 2026 Quarterly Rebalance PRICE SENSITIVE
2026-09-03 Investor Webinar Presentation Q3 2026
2026-09-02 ADOA Program - Data Presentation
2026-09-02 Ceasing to be a substantial holder
2026-08-30 PKD - Presentation of Clinical Safety Data

Key Metrics

$2.5B
Market Cap
3.3M
Avg Volume
1.6x
Vol Ratio
$0.85 — $2.62
52-Week Range
0.1%
Short Interest
N/A
Cash Runway
-10.1%
ROE
-166.7%
Profit Margin

CANSLIM Analysis

FactorRatingDetail
CCurrent EPSfailEPS Growth: 0%
AAnnual EarningsfailCAGR: 0%
NNew Highs / CatalystspassNear 52w High
SSupply & DemandneutralFloat: 64%
LLeader vs LaggardpassRS: 40
IInstitutional SponsorshippassInst: 16%
MMarket DirectionneutralNeutral

Sector: Healthcare

110 tickers in this sector

View all Healthcare signals →Browse all ASX tickers A–Z →
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Compare:PYC vs NUZPYC vs IPDPYC vs HIQ
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